Byron Goldstein

From BioNetWiki

Recent Publications

C. Wofsy, D. Coombs and B. Goldstein (2001). Calculations show substantial serial engagement of T cell receptors. Biophys. J. 80:606-612.

W. S. Hlavacek, A. Redondo, H. Metzger, C. Wofsy and B. Goldstein (2001). Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading. Proc. Natl. Acad. Sci. USA 98:7295-7300.

S. Lauer, B. Goldstein, R. L. Nolan and J. P. Nolan (2002). Analysis of cholera toxin-ganglioside interactions by flow cytometry. Biochemistry 41:1742-1751.

S. F. Liparoto, D. G. Myszka, Z. Wu, B. Goldstein, T. M. Laue and T. Ciardelli (2002). Analysis of the role of interleukin-2 receptor gamma chain in ligand binding. Biochemistry 41:2543-2551.

C. Wofsy and B. Goldstein (2002). Effective rate models for receptors distributed in a Layer above a surface: application to cells and BIACORE. Biophys. J. 82:1743-1755.

B. Goldstein, J. R. Faeder, W. S. Hlavacek, M. L. Blinov, A. Redondo, and C. Wofsy (2002). Modeling the Early Signaling Events Mediated by FcεRI. Mol. Immunol. 38:1213-1219.

W. S. Hlavacek, A. Redondo, C. Wofsy and B. Goldstein (2002). Kinetic proofreading in receptor-mediated transduction of cellular signals. Bull. Math. Biol. 64:887-911.

D. Coombs, A. M. Kalergis, S. G. Nathenson, C. Wofsy and B. Goldstein (2002). Activated TCR remain marked for internalization after dissociation from peptide-MHC. Nature Immunol. 3:926-931.

J. R. Faeder, W. S. Hlavacek, I. Reischl, M. L. Blinov, H. Metzger, A. Redondo, C. Wofsy and B. Goldstein (2003). Investigation of early events in FcεRI-mediated signaling using a detailed mathematical model. J. Immunol. 170:3769-3781.

W. S. Hlavacek, J. R. Faeder, M. L. Blinov, A. S. Perelson and B. Goldstein (2003). The complexity of complexes in signal transduction. Biotech. Bioeng. 84:784-794.

D. Coombs, M. Dembo, M., C. Wofsy, and B. Goldstein. (2004). Equilibrium thermodynamics of cell-cell adhesion mediated by multiple ligand-receptor pairs. Biophys. J. 86:1408-1423.

B. Goldstein, J. R. Faeder and W. S. Hlavacek (2004). Mathematical models of immune receptor signaling. Nature Reviews Immunol. 4:445-456.

D. Coombs and B. Goldstein (2004). Effects of the geometry of the immunological synapse on the delivery of effector molecules. Biophys. J. 87: 2215-2220.

M. Blinov, J. R. Faeder, B. Goldstein and W. S. Hlavacek (2004). BioNetGen: software for rule-based modeling of signaling transduction based on the interactions of molecular domains. Bioinformatics 20, 3289-3291.

J. R. Faeder, M. L. Blinov, B. Goldstein and W. S. Hlavacek (2004). Ruled-based modeling of biochemical networks. Complexity 10, 22-41.

P. A. Gonzalez, L. J. Carreno, D. Coombs, J. E. Mora, E. Palmieri, B. Goldstein, S. G. Nathenson and A. M. Kalergis (2005). Effects of pMHC and TCR dwell time on T cell activation. Proc. Natl. Acad. Sci. USA 102, 4824-4829.

Faeder, J.R., M. L. Blinov, B. Goldstein and W. S. Hlavacek (2005). Combinatorial complexity and dynamical restriction of network flows in signal transduction. Systems Biology 2, 5-15.

D. Coombs and B. Goldstein (2005). T cell activation: Kinetic proofreading, serial engagement and cell adhesion. J. Comput. Appl. Math. (Special Issue on Mathematics Applied to Immunology - Edited by G. Bocharov, H. Brunner, Z. Grossman.) 184, 121-139.

M. L. Blinov, J. R. Faeder, B. Goldstein and W. S. Hlavacek (2006). A network model of early events in epidermal growth factor signaling that accounts for combinatorial complexity. BioSystems 83, 136-151.

X. He, D. Coombs, D. G. Myszka and B. Goldstein. A theoretical and experimental study of the competition for ligand in a Biacore flow cell (2006). Bull. Math. Biol. 68, 1125-1150.

C. Torgioe, J. R. Faeder, J. M. Oliver and B. Goldstein (2007). Kinetic proofreading of ligand-FcεRI interactions may persists beyond LAT phosphorylation. J. Immunol. 178, 3530-3535.

B. Goldstein, H. Levine and D. Torney (2007). Diffusion limited reaction. SIAM J. APPL. MATH. 67, 1147-1165.

K. W. Wucherpfennig, P. M. Allen, F. Celada, I. R. Cohen, R. De Boer, K. C. Garcia, B. Goldstein, R. Greenspan, D. Hafler, P. Hodgkin, E. S. Huseby, D. Krakauer, D. Nemazee, A. S. Perelson, C. Pinilla, R. K. Strong and E. Sercarz (2007). Polyspecificity of T cell and B cell receptor recognition. Seminars in Immunol. 19, 216-224.

M. L. Dustin, T. Starr, D. Coombs, G. R. Majeau, W. Meier, P. S. Hochman, A. Douglass, R. Vale, B. Goldstein and A. Whitty (2007). Quantification and modeling of tripartite CD2, CD58FC chiera (Alefacept) and CD16 mediated cell adhesion. J. Cell Biol. 282, 34748-34757.

B. Goldstein, D. Coombs, J. R. Faeder and W. S. Hlavacek (2008). Kinetic Proofreading Model. Adv. Exp. Med. Biol. 640, 82-94. In: Multichain Immune Recognition Receptor Signaling: From Spatiotemporal Organization to Human Disease (A.B. Sigalov, Editor), Ch. 8. Landes Bioscience, Austin, TX. (ISBN: 978-0-387-09788-6)

R. Das, E. Baird, S. Allen, B. Baird, D. Holowka and B. Goldstein (2008). Binding mechanisms of PEGylated ligands reveal multiple effects of PEG scaffold. Biochemistry 47, 1017-1030.

S. Lauer, Y. A. Kunde, T. A. Apodaca, B. Goldstein and E. Hong-Geller (2009). Soluble MD2 increases TLR4 Levels on the epithelial cell surface. Cell. Immunol. 225, 8-16.

A. Nag, M. I. Monine, J. R. Faeder and B. Goldstein (2009). Aggregation of membrane proteins by cytosolic cross-linkers: Theory and simulation of the LAT-Grb2-SOS1 system. Biophys. J. 96, 2604-2623.